Endocrine Abstracts

Perfluorooctanesulfonate (PFOS) and its related product perfluorooctanic acid (PFOA) are anthropogenic fluorosurfactants widely used in consumer products. In general, studies in rodents have supported the conception that PFOS perturbs testis function, such as by inducing Sertoli cell injury. It remains to be demonstrated if similar effects could be reproduced in humans. We sought to examine its effects on human spermatogenesis by using a human Sertoli cell primary culture syst...